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Increased Sensitivity to Inflammatory Pain Induced by Subcutaneous Formalin Injection in Serine Racemase Knock-Out Mice

D-Serine, an endogenous coagonist of the N-methyl-D-aspartate receptor (NMDAR), is widely distributed in the central nervous system and is synthesized from L-serine by serine racemase (SR). NMDAR plays an important role in pain processing including central sensitization that eventually causes hypera...

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Detalles Bibliográficos
Autores principales: Tabata-Imai, Ayako, Inoue, Ran, Mori, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136830/
https://www.ncbi.nlm.nih.gov/pubmed/25133605
http://dx.doi.org/10.1371/journal.pone.0105282