Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice

Our previous study showed that besides mRNAs and microRNAs, there are DNA fragments within extracellular vesicles (EVs). The BCR/ABL hybrid gene, involved in the pathogenesis of chronic myeloid leukemia (CML), could be transferred from K562 EVs to neutrophils and decrease their phagocytic activity i...

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Detalles Bibliográficos
Autores principales: Cai, Jin, Wu, Gengze, Tan, Xiaorong, Han, Yu, Chen, Caiyu, Li, Chuanwei, Wang, Na, Zou, Xue, Chen, Xinjian, Zhou, Faying, He, Duofen, Zhou, Lin, Jose, Pedro A., Zeng, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136837/
https://www.ncbi.nlm.nih.gov/pubmed/25133686
http://dx.doi.org/10.1371/journal.pone.0105200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136837/
https://www.ncbi.nlm.nih.gov/pubmed/25133686
http://dx.doi.org/10.1371/journal.pone.0105200

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