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Molecular Dynamics Study of Binding of µ-Conotoxin GIIIA to the Voltage-Gated Sodium Channel Na(v)1.4

Homology models of mammalian voltage-gated sodium (Na(V)) channels based on the crystal structures of the bacterial counterparts are needed to interpret the functional data on sodium channels and understand how they operate. Such models would also be invaluable in structure-based design of therapeut...

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Detalles Bibliográficos
Autores principales: Mahdavi, Somayeh, Kuyucak, Serdar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136838/
https://www.ncbi.nlm.nih.gov/pubmed/25133704
http://dx.doi.org/10.1371/journal.pone.0105300