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Is Thymidine Glycol Containing DNA a Substrate of E. coli DNA Mismatch Repair System?

The DNA mismatch repair (MMR) system plays a crucial role in the prevention of replication errors and in the correction of some oxidative damages of DNA bases. In the present work the most abundant oxidized pyrimidine lesion, 5,6-dihydro-5,6-dihydroxythymidine (thymidine glycol, Tg) was tested for b...

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Detalles Bibliográficos
Autores principales: Perevozchikova, Svetlana A., Trikin, Roman M., Heinze, Roger J., Romanova, Elena A., Oretskaya, Tatiana S., Friedhoff, Peter, Kubareva, Elena A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136841/
https://www.ncbi.nlm.nih.gov/pubmed/25133614
http://dx.doi.org/10.1371/journal.pone.0104963