Sirt1 and Sirt6 Mediate Beneficial Effects of Rosiglitazone on Hepatic Lipid Accumulation

BACKGROUND: Sirtuin (Sirt), a sensor of the cell metabolic state, regulates glucose and lipid metabolism. The aim of this study was to address whether rosiglitazone (RGZ) alters hepatic Sirt1 and whether Sirt1 and/or Sirt6 have a regulatory role in the protective effects of RGZ on hepatocyte steatos...

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Detalles Bibliográficos
Autores principales: Yang, Soo Jin, Choi, Jung Mook, Chang, Eugene, Park, Sung Woo, Park, Cheol-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136882/
https://www.ncbi.nlm.nih.gov/pubmed/25133775
http://dx.doi.org/10.1371/journal.pone.0105456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136882/
https://www.ncbi.nlm.nih.gov/pubmed/25133775
http://dx.doi.org/10.1371/journal.pone.0105456

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