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Mst1 Directs Myosin IIa Partitioning of Low and Higher Affinity Integrins during T Cell Migration

Chemokines promote T cell migration by transmitting signals that induce T cell polarization and integrin activation and adhesion. Mst1 kinase is a key signal mediator required for both of these processes; however, its molecular mechanism remains unclear. Here, we present a mouse model in which Mst1...

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Detalles Bibliográficos
Autores principales: Xu, Xiaolu, Jaeger, Emily R., Wang, Xinxin, Lagler-Ferrez, Erica, Batalov, Serge, Mathis, Nancy L., Wiltshire, Tim, Walker, John R., Cooke, Michael P., Sauer, Karsten, Huang, Yina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136924/
https://www.ncbi.nlm.nih.gov/pubmed/25133611
http://dx.doi.org/10.1371/journal.pone.0105561