Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery

Phosphorylation of replication protein A (RPA) by Cdk2 and the checkpoint kinase ATR (ATM and Rad3 related) during replication fork stalling stabilizes the replisome, but how these modifications safeguard the fork is not understood. To address this question, we used single-molecule fiber analysis in...

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Detalles Bibliográficos
Autores principales: Murphy, Anar K., Fitzgerald, Michael, Ro, Teresa, Kim, Jee Hyun, Rabinowitsch, Ariana I., Chowdhury, Dipanjan, Schildkraut, Carl L., Borowiec, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137056/
https://www.ncbi.nlm.nih.gov/pubmed/25113031
http://dx.doi.org/10.1083/jcb.201404111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137056/
https://www.ncbi.nlm.nih.gov/pubmed/25113031
http://dx.doi.org/10.1083/jcb.201404111

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