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A phenome-guided drug repositioning through a latent variable model

BACKGROUND: The phenome represents a distinct set of information in the human population. It has been explored particularly in its relationship with the genome to identify correlations for diseases. The phenome has been also explored for drug repositioning with efforts focusing on the search space f...

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Detalles Bibliográficos
Autores principales: Bisgin, Halil, Liu, Zhichao, Fang, Hong, Kelly, Reagan, Xu, Xiaowei, Tong, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137076/
https://www.ncbi.nlm.nih.gov/pubmed/25103881
http://dx.doi.org/10.1186/1471-2105-15-267