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A phenome-guided drug repositioning through a latent variable model
BACKGROUND: The phenome represents a distinct set of information in the human population. It has been explored particularly in its relationship with the genome to identify correlations for diseases. The phenome has been also explored for drug repositioning with efforts focusing on the search space f...
Autores principales: | Bisgin, Halil, Liu, Zhichao, Fang, Hong, Kelly, Reagan, Xu, Xiaowei, Tong, Weida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137076/ https://www.ncbi.nlm.nih.gov/pubmed/25103881 http://dx.doi.org/10.1186/1471-2105-15-267 |
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