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Polyploid giant cancer cells with budding and the expression of cyclin E, S-phase kinase-associated protein 2, stathmin associated with the grading and metastasis in serous ovarian tumor

BACKGROUND: We previously reported that polyploid giant cancer cells (PGCCs) exhibit cancer stem cell properties and express cell cycle-related proteins. HEY PGCCs induced by cobalt chloride generated daughter cells and the daughter cells had a strong migratory and invasive ability. This study is to...

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Detalles Bibliográficos
Autores principales: Lv, Hongcheng, Shi, Yang, Zhang, Li, Zhang, Dan, Liu, Guang, Yang, Zhengduo, Li, Yan, Fei, Fei, Zhang, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137091/
https://www.ncbi.nlm.nih.gov/pubmed/25106448
http://dx.doi.org/10.1186/1471-2407-14-576