Impact of a functional polymorphism in the PAR-1 gene promoter in COPD and COPD exacerbations

Proteinase-activated receptor-1 (PAR-1) plays a key role in mediating the interplay between coagulation and inflammation in response to injury. The aim of this study was to investigate the role of the promoter single-nucleotide polymorphism (SNP) rs2227744G>A in modulating PAR-1/F2R gene expressi...

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Detalles Bibliográficos
Autores principales: Platé, Manuela, Lawson, Phillippa J., Hill, Michael R., Quint, Jennifer K., Kumari, Meena, Laurent, Geoffrey J., Wedzicha, Jadwiga A., Chambers, Rachel C., Hurst, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137163/
https://www.ncbi.nlm.nih.gov/pubmed/24973402
http://dx.doi.org/10.1152/ajplung.00128.2014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137163/
https://www.ncbi.nlm.nih.gov/pubmed/24973402
http://dx.doi.org/10.1152/ajplung.00128.2014

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