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Impact of a functional polymorphism in the PAR-1 gene promoter in COPD and COPD exacerbations
Proteinase-activated receptor-1 (PAR-1) plays a key role in mediating the interplay between coagulation and inflammation in response to injury. The aim of this study was to investigate the role of the promoter single-nucleotide polymorphism (SNP) rs2227744G>A in modulating PAR-1/F2R gene expressi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Physiological Society
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137163/ https://www.ncbi.nlm.nih.gov/pubmed/24973402 http://dx.doi.org/10.1152/ajplung.00128.2014 |