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Bidirectional helical motility of cytoplasmic dynein around microtubules

Cytoplasmic dynein is a molecular motor responsible for minus-end-directed cargo transport along microtubules (MTs). Dynein motility has previously been studied on surface-immobilized MTs in vitro, which constrains the motors to move in two dimensions. In this study, we explored dynein motility in t...

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Detalles Bibliográficos
Autores principales: Can, Sinan, Dewitt, Mark A, Yildiz, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137274/
https://www.ncbi.nlm.nih.gov/pubmed/25069614
http://dx.doi.org/10.7554/eLife.03205