Most genetic risk for autism resides with common variation

A key component of genetic architecture is the allelic spectrum influencing trait variability. For autism spectrum disorder (henceforth autism) the nature of its allelic spectrum is uncertain. Individual risk genes have been identified from rare variation, especially de novo mutations(1–8). From thi...

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Detalles Bibliográficos
Autores principales: Gaugler, Trent, Klei, Lambertus, Sanders, Stephan J., Bodea, Corneliu A., Goldberg, Arthur P., Lee, Ann B., Mahajan, Milind, Manaa, Dina, Pawitan, Yudi, Reichert, Jennifer, Ripke, Stephan, Sandin, Sven, Sklar, Pamela, Svantesson, Oscar, Reichenberg, Abraham, Hultman, Christina M., Devlin, Bernie, Roeder, Kathryn, Buxbaum, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137411/
https://www.ncbi.nlm.nih.gov/pubmed/25038753
http://dx.doi.org/10.1038/ng.3039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137411/
https://www.ncbi.nlm.nih.gov/pubmed/25038753
http://dx.doi.org/10.1038/ng.3039

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