Rethinking Molecular Mimicry in Rheumatic Heart Disease and Autoimmune Myocarditis: Laminin, Collagen IV, CAR, and B1AR as Initial Targets of Disease

Rationale: Molecular mimicry theory (MMT) suggests that epitope mimicry between pathogens and human proteins can activate autoimmune disease. Group A streptococci (GAS) mimics human cardiac myosin in rheumatic heart disease (RHD) and coxsackie viruses (CX) mimic actin in autoimmune myocarditis (AM)....

Descripción completa

Detalles Bibliográficos
Autor principal: Root-Bernstein, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137453/
https://www.ncbi.nlm.nih.gov/pubmed/25191648
http://dx.doi.org/10.3389/fped.2014.00085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137453/
https://www.ncbi.nlm.nih.gov/pubmed/25191648
http://dx.doi.org/10.3389/fped.2014.00085

Ejemplares similares