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Transgenic Rat Model of Huntington's Disease: A Histopathological Study and Correlations with Neurodegenerative Process in the Brain of HD Patients

Rats transgenic for Huntington's disease (tgHD51 CAG rats), surviving up to two years, represent an animal model of HD similar to the late-onset form of human disease. This enables us to follow histopathological changes in course of neurodegenerative process (NDP) within the striatum and compar...

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Detalles Bibliográficos
Autores principales: Mazurová, Yvona, Anderova, Miroslava, Němečková, Ivana, Bezrouk, Aleš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137602/
https://www.ncbi.nlm.nih.gov/pubmed/25162006
http://dx.doi.org/10.1155/2014/291531