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Strength of Selection Pressure Is an Important Parameter Contributing to the Complexity of Antibiotic Resistance Evolution

Revealing the genetic changes responsible for antibiotic resistance can be critical for developing novel antibiotic therapies. However, systematic studies correlating genotype to phenotype in the context of antibiotic resistance have been missing. In order to fill in this gap, we evolved 88 isogenic...

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Detalles Bibliográficos
Autores principales: Oz, Tugce, Guvenek, Aysegul, Yildiz, Sadik, Karaboga, Enes, Tamer, Yusuf Talha, Mumcuyan, Nirva, Ozan, Vedat Burak, Senturk, Gizem Hazal, Cokol, Murat, Yeh, Pamela, Toprak, Erdal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137714/
https://www.ncbi.nlm.nih.gov/pubmed/24962091
http://dx.doi.org/10.1093/molbev/msu191