Cargando…
Strength of Selection Pressure Is an Important Parameter Contributing to the Complexity of Antibiotic Resistance Evolution
Revealing the genetic changes responsible for antibiotic resistance can be critical for developing novel antibiotic therapies. However, systematic studies correlating genotype to phenotype in the context of antibiotic resistance have been missing. In order to fill in this gap, we evolved 88 isogenic...
Autores principales: | Oz, Tugce, Guvenek, Aysegul, Yildiz, Sadik, Karaboga, Enes, Tamer, Yusuf Talha, Mumcuyan, Nirva, Ozan, Vedat Burak, Senturk, Gizem Hazal, Cokol, Murat, Yeh, Pamela, Toprak, Erdal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137714/ https://www.ncbi.nlm.nih.gov/pubmed/24962091 http://dx.doi.org/10.1093/molbev/msu191 |
Ejemplares similares
-
High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection
por: Tamer, Yusuf Talha, et al.
Publicado: (2019) -
The Antibiotic Efflux Protein TolC Is a Highly Evolvable Target under Colicin E1 or TLS Phage Selection
por: Tamer, Yusuf Talha, et al.
Publicado: (2021) -
Quantifying the Determinants of Evolutionary Dynamics Leading to Drug Resistance
por: Chevereau, Guillaume, et al.
Publicado: (2015) -
Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy
por: Ayhan, Dilay Hazal, et al.
Publicado: (2016) -
Rapid ultrasensitive detection platform for antimicrobial susceptibility testing
por: Cansizoglu, Mehmet F., et al.
Publicado: (2019)