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The effects of tramadol on norepinephrine and MHPG releasing in locus coeruleus in formalin test in rats: a brain stereotaxic study

OBJECTIVE(S): The relationship between tramadol, as an antinociceptive drug, and locus coeruleus (LC), the main noradrenergic nucleus of the brain that affects regulation and modulation of pain through descending noradrenergic pathways was investigated. MATERIALS AND METHODS: Male Sprague-Dawley rat...

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Detalles Bibliográficos
Autores principales: Mobasher, Mohammad Ali, Sajedianfard, Javad, Jamshidzadeh, Akram, Naghdi, Naser, Namvaran, Mohammad Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137945/
https://www.ncbi.nlm.nih.gov/pubmed/25140203