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1α,25-dihydroxyvitamin D3 in combination with transforming growth factor-β increases the frequency of Foxp3(+) regulatory T cells through preferential expansion and usage of interleukin-2
A high prevalence of vitamin D insufficiency and deficiency exists worldwide, which is associated with an increased incidence and severity of a range of immune-mediated diseases. This has resulted in considerable interest in the immunodulatory functions of vitamin D. The active form of vitamin D, 1α...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137955/ https://www.ncbi.nlm.nih.gov/pubmed/24673126 http://dx.doi.org/10.1111/imm.12289 |