Signal-regulatory protein α from the NOD mouse binds human CD47 with an exceptionally high affinity – implications for engraftment of human cells

One common way to study human leucocytes and cancer cells in an experimental in vivo situation is to use mice that have been genetically engineered to lack an immune system and prevent human cell rejection. These mice lack CD132 and either RAG2 or the catalytic subunit of the DNA-dependent protein k...

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Detalles Bibliográficos
Autores principales: Kwong, Lai Shan, Brown, Marion H, Barclay, A Neil, Hatherley, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137956/
https://www.ncbi.nlm.nih.gov/pubmed/24786312
http://dx.doi.org/10.1111/imm.12290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137956/
https://www.ncbi.nlm.nih.gov/pubmed/24786312
http://dx.doi.org/10.1111/imm.12290

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