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Modeling Viral Evolutionary Dynamics after Telaprevir-Based Treatment

For patients infected with hepatitis C virus (HCV), the combination of the direct-acting antiviral agent telaprevir, pegylated-interferon alfa (Peg-IFN), and ribavirin (RBV) significantly increases the chances of sustained virologic response (SVR) over treatment with Peg-IFN and RBV alone. If patien...

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Detalles Bibliográficos
Autores principales: Haseltine, Eric L., De Meyer, Sandra, Dierynck, Inge, Bartels, Doug J., Ghys, Anne, Davis, Andrew, Zhang, Eileen Z., Tigges, Ann M., Spanks, Joan, Picchio, Gaston, Kieffer, Tara L., Sullivan, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138032/
https://www.ncbi.nlm.nih.gov/pubmed/25101970
http://dx.doi.org/10.1371/journal.pcbi.1003772