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Modeling Viral Evolutionary Dynamics after Telaprevir-Based Treatment
For patients infected with hepatitis C virus (HCV), the combination of the direct-acting antiviral agent telaprevir, pegylated-interferon alfa (Peg-IFN), and ribavirin (RBV) significantly increases the chances of sustained virologic response (SVR) over treatment with Peg-IFN and RBV alone. If patien...
Autores principales: | Haseltine, Eric L., De Meyer, Sandra, Dierynck, Inge, Bartels, Doug J., Ghys, Anne, Davis, Andrew, Zhang, Eileen Z., Tigges, Ann M., Spanks, Joan, Picchio, Gaston, Kieffer, Tara L., Sullivan, James C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138032/ https://www.ncbi.nlm.nih.gov/pubmed/25101970 http://dx.doi.org/10.1371/journal.pcbi.1003772 |
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