NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

BACKGROUND: Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM). We aimed to explore whether NLRP3 inflammasome activation contributes to DCM and the...

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Detalles Bibliográficos
Autores principales: Luo, Beibei, Li, Bo, Wang, Wenke, Liu, Xiangjuan, Xia, Yanfei, Zhang, Cheng, Zhang, Mingxiang, Zhang, Yun, An, Fengshuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138036/
https://www.ncbi.nlm.nih.gov/pubmed/25136835
http://dx.doi.org/10.1371/journal.pone.0104771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138036/
https://www.ncbi.nlm.nih.gov/pubmed/25136835
http://dx.doi.org/10.1371/journal.pone.0104771

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