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NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model
BACKGROUND: Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM). We aimed to explore whether NLRP3 inflammasome activation contributes to DCM and the...
Autores principales: | Luo, Beibei, Li, Bo, Wang, Wenke, Liu, Xiangjuan, Xia, Yanfei, Zhang, Cheng, Zhang, Mingxiang, Zhang, Yun, An, Fengshuang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138036/ https://www.ncbi.nlm.nih.gov/pubmed/25136835 http://dx.doi.org/10.1371/journal.pone.0104771 |
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