Cargando…

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

BACKGROUND: Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM). We aimed to explore whether NLRP3 inflammasome activation contributes to DCM and the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Beibei, Li, Bo, Wang, Wenke, Liu, Xiangjuan, Xia, Yanfei, Zhang, Cheng, Zhang, Mingxiang, Zhang, Yun, An, Fengshuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138036/ https://www.ncbi.nlm.nih.gov/pubmed/25136835 http://dx.doi.org/10.1371/journal.pone.0104771

Ejemplares similares

TRB3 Gene Silencing Alleviates Diabetic Cardiomyopathy in a Type 2 Diabetic Rat Model
por: Ti, Yun, et al.
Publicado: (2011)

NLRP3 Inflammasome as a Molecular Marker in Diabetic Cardiomyopathy
por: Luo, Beibei, et al.
Publicado: (2017)

Combination of angiotensin-(1–7) with perindopril is better than single therapy in ameliorating diabetic cardiomyopathy
por: Hao, Panpan, et al.
Publicado: (2015)

Chemerin/CMKLR1 Axis Promotes Inflammation and Pyroptosis by Activating NLRP3 Inflammasome in Diabetic Cardiomyopathy Rat
por: Xie, Yebin, et al.
Publicado: (2020)

Cyclovirobuxine D Ameliorates Experimental Diabetic Cardiomyopathy by Inhibiting Cardiomyocyte Pyroptosis via NLRP3 in vivo and in vitro
por: Gao, Ge, et al.
Publicado: (2022)

Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes
por: Sun, Xiaoxiao, et al.
Publicado: (2019)

Gypenosides improve diabetic cardiomyopathy by inhibiting ROS‐mediated NLRP3 inflammasome activation
por: Zhang, Hailong, et al.
Publicado: (2018)

Inhibition of PHLPP1 ameliorates cardiac dysfunction via activation of the PI3K/Akt/mTOR signalling pathway in diabetic cardiomyopathy
por: Zhang, Mingjun, et al.
Publicado: (2020)

NLRP3 Inflammasome in Diabetic Cardiomyopathy and Exercise Intervention
por: Sun, Yi, et al.
Publicado: (2021)

NLRP3 Inflammasome/Pyroptosis: A Key Driving Force in Diabetic Cardiomyopathy
por: Zhang, Lixia, et al.
Publicado: (2022)

Relaxin-3 Ameliorates Diabetic Cardiomyopathy by Inhibiting Endoplasmic Reticulum Stress
por: Pan, Li-ya, et al.
Publicado: (2022)

Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway
por: Wang, Xuyang, et al.
Publicado: (2019)

Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus
por: Wang, Yao, et al.
Publicado: (2017)

Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats
por: Al-Rasheed, Nawal M., et al.
Publicado: (2017)

Urocortin ameliorates diabetic cardiomyopathy in rats via the Akt/GSK-3β signaling pathway
por: LIU, XINYU, et al.
Publicado: (2015)

PDCD4 deficiency ameliorates left ventricular remodeling and insulin resistance in a rat model of type 2 diabetic cardiomyopathy
por: Zhang, Jie, et al.
Publicado: (2020)

BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity
por: Yu, Xiao-Jun, et al.
Publicado: (2023)

Myocardial Protective Effects of Nicorandil on Rats with Type 2 Diabetic Cardiomyopathy
por: Zhang, Meng, et al.
Publicado: (2018)

The Role of NLRP3 Inflammasome in Diabetic Cardiomyopathy and Its Therapeutic Implications
por: Ding, Kai, et al.
Publicado: (2022)

Berberine Could Ameliorate Cardiac Dysfunction via Interfering Myocardial Lipidomic Profiles in the Rat Model of Diabetic Cardiomyopathy
por: Dong, Shifen, et al.
Publicado: (2018)

Silencing of NOD2 protects against diabetic cardiomyopathy in a murine diabetes model
por: Shen, Lin, et al.
Publicado: (2018)

Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation in vitro and in vivo
por: Li, Yuan, et al.
Publicado: (2022)

Silencing of miR-150-5p Ameliorates Diabetic Nephropathy by Targeting SIRT1/p53/AMPK Pathway
por: Dong, Wenmin, et al.
Publicado: (2021)

Metformin Ameliorates Diabetic Cardiomyopathy by Activating the PK2/PKR Pathway
por: Yang, Zhen, et al.
Publicado: (2020)

Overexpression of complement component C5a accelerates the development of atherosclerosis in ApoE-knockout mice
por: An, Guipeng, et al.
Publicado: (2016)

Attenuation of ROS/Chloride Efflux-Mediated NLRP3 Inflammasome Activation Contributes to Alleviation of Diabetic Cardiomyopathy in Rats after Sleeve Gastrectomy
por: Li, Songhan, et al.
Publicado: (2022)

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling
por: Lu, Miaomiao, et al.
Publicado: (2017)

Inhibition of NLRP3 Inflammasome Ameliorates Cerebral Ischemia-Reperfusion Injury in Diabetic Mice
por: Hong, Pu, et al.
Publicado: (2018)

Rutin alleviates diabetic cardiomyopathy in a rat model of type 2 diabetes
por: WANG, YONG-BIN, et al.
Publicado: (2015)

Distinct Types of Cell Death and the Implication in Diabetic Cardiomyopathy
por: Chen, Yun, et al.
Publicado: (2020)

Jinmaitong Ameliorates Diabetic Peripheral Neuropathy Through Suppressing TXNIP/NLRP3 Inflammasome Activation In The Streptozotocin-Induced Diabetic Rat Model
por: Sun, Qing, et al.
Publicado: (2019)

Cardiomyocyte-specific knockout of ADAM17 ameliorates left ventricular remodeling and function in diabetic cardiomyopathy of mice
por: Xue, Fei, et al.
Publicado: (2022)

Aloe-Emodin Derivative, an Anthraquinone Compound, Attenuates Pyroptosis by Targeting NLRP3 Inflammasome in Diabetic Cardiomyopathy
por: Hu, Yingying, et al.
Publicado: (2023)

Irbesartan ameliorates myocardial fibrosis in diabetic cardiomyopathy rats by inhibiting the TGFβ1/Smad2/3 pathway
por: Zong, Min, et al.
Publicado: (2020)

Salvianolic Acid A Ameliorates Early-Stage Atherosclerosis Development by Inhibiting NLRP3 Inflammasome Activation in Zucker Diabetic Fatty Rats
por: Ma, Quanxin, et al.
Publicado: (2020)

Systemic Delivery of siRNA Specific for Silencing TLR4 Gene Expression Reduces Diabetic Cardiomyopathy in a Mouse Model of Streptozotocin-Induced Type 1 Diabetes
por: Zhang, Yuwei, et al.
Publicado: (2020)

The Protective Effect of Sheng Mai Yin on Diabetic Cardiomyopathy via NLRP3/Caspase-1 Pathway
por: Li, Jing-Ya, et al.
Publicado: (2022)

Exercise Ameliorates Diabetic Kidney Disease in Type 2 Diabetic Fatty Rats
por: Monno, Itaru, et al.
Publicado: (2021)

Mesenchymal stem cells promote type 2 macrophage polarization to ameliorate the myocardial injury caused by diabetic cardiomyopathy
por: Jin, Liyuan, et al.
Publicado: (2019)

Finerenone attenuates myocardial apoptosis, metabolic disturbance and myocardial fibrosis in type 2 diabetes mellitus
por: Jin, Tao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_lqd3vutgd6p4tigrshkpitenhs