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Exenatide Treatment Exerts Anxiolytic- and Antidepressant-Like Effects and Reverses Neuropathy in a Mouse Model of Type-2 Diabetes

BACKGROUND: Comorbid neurobehavioral disturbances and type-2 diabetes mellitus (T2DM) warrant immediate research attention. Exenatide, which is a potent and selective agonist for the glucagon-like peptide-1 (GLP-1), is used in the treatment of T2DM. Exenatide displays a multitude of effects in the c...

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Detalles Bibliográficos
Autores principales: Celikyurt, Ipek Komsuoglu, Mutlu, Oguz, Ulak, Guner, Uyar, Emre, Bektaş, Emine, Akar, Furuzan Yildiz, Erden, Faruk, Tarkun, Ilhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138071/
https://www.ncbi.nlm.nih.gov/pubmed/25076419
http://dx.doi.org/10.12659/MSMBR.891168