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Induction of Highly Functional Hepatocytes from Human Umbilical Cord Mesenchymal Stem Cells by HNF4α Transduction

AIM: To investigate the differentiation potential of human umbilical mesenchymal stem cells (HuMSCs) and the key factors that facilitate hepatic differentiation. METHODS: HuMSCs were induced to become hepatocyte-like cells according to a previously published protocol. The differentiation status of t...

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Detalles Bibliográficos
Autores principales: Hang, Hualian, Yu, Yabin, Wu, Ning, Huang, Qingfeng, Xia, Qiang, Bian, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138090/
https://www.ncbi.nlm.nih.gov/pubmed/25137413
http://dx.doi.org/10.1371/journal.pone.0104133