The Flavones Apigenin and Luteolin Induce FOXO1 Translocation but Inhibit Gluconeogenic and Lipogenic Gene Expression in Human Cells

The flavones apigenin (4′,5,7,-trihydroxyflavone) and luteolin (3′,4′,5,7,-tetrahydroxyflavone) are plant secondary metabolites with antioxidant, antiinflammatory, and anticancer activities. We evaluated their impact on cell signaling pathways related to insulin-resistance and type 2 diabetes. Apige...

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Detalles Bibliográficos
Autores principales: Bumke-Vogt, Christiane, Osterhoff, Martin A., Borchert, Andrea, Guzman-Perez, Valentina, Sarem, Zeinab, Birkenfeld, Andreas L., Bähr, Volker, Pfeiffer, Andreas F. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138109/
https://www.ncbi.nlm.nih.gov/pubmed/25136826
http://dx.doi.org/10.1371/journal.pone.0104321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138109/
https://www.ncbi.nlm.nih.gov/pubmed/25136826
http://dx.doi.org/10.1371/journal.pone.0104321

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