An E2F1-HOXB9 Transcriptional Circuit Is Associated with Breast Cancer Progression

Homeobox B9 (HOXB9), a member of the homeobox gene family, is overexpressed in breast cancer and promotes tumor progression and metastasis by stimulating epithelial-to-mesenchymal transition and angiogenesis within the tumor microenvironment. HOXB9 activates the TGFβ-ATM axis, leading to checkpoint...

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Detalles Bibliográficos
Autores principales: Zhussupova, Aisulu, Hayashida, Tetsu, Takahashi, Maiko, Miyao, Kazuhiro, Okazaki, Hiroshi, Jinno, Hiromitsu, Kitagawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138122/
https://www.ncbi.nlm.nih.gov/pubmed/25136922
http://dx.doi.org/10.1371/journal.pone.0105285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138122/
https://www.ncbi.nlm.nih.gov/pubmed/25136922
http://dx.doi.org/10.1371/journal.pone.0105285

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