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High IL-17E and Low IL-17C Dermal Expression Identifies a Fibrosis-Specific Motif Common to Morphea and Systemic Sclerosis

BACKGROUND: High interleukin (IL)-17A levels are characteristically found in the skin of systemic sclerosis (SSc) individuals. Our aim was to investigate whether the dermal expression of IL-17A and related IL-17 family members (i.e. IL-17C, IL-17E and IL-17F) could distinguish fibrotic from healthy...

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Detalles Bibliográficos
Autores principales: Lonati, Paola Adele, Brembilla, Nicolò Costantino, Montanari, Elisa, Fontao, Lionel, Gabrielli, Armando, Vettori, Serena, Valentini, Gabriele, Laffitte, Emmanuel, Kaya, Gurkan, Meroni, Pier-Luigi, Chizzolini, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138152/
https://www.ncbi.nlm.nih.gov/pubmed/25136988
http://dx.doi.org/10.1371/journal.pone.0105008