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A Quantitative Comparison of Single-Cell Whole Genome Amplification Methods

Single-cell sequencing is emerging as an important tool for studies of genomic heterogeneity. Whole genome amplification (WGA) is a key step in single-cell sequencing workflows and a multitude of methods have been introduced. Here, we compare three state-of-the-art methods on both bulk and single-ce...

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Detalles Bibliográficos
Autores principales: de Bourcy, Charles F. A., De Vlaminck, Iwijn, Kanbar, Jad N., Wang, Jianbin, Gawad, Charles, Quake, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138190/
https://www.ncbi.nlm.nih.gov/pubmed/25136831
http://dx.doi.org/10.1371/journal.pone.0105585