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CDK11(p58) inhibits ERα-positive breast cancer invasion by targeting integrin β3 via the repression of ERα signaling
BACKGROUND: CDK11(p58), a Ser/Thr kinase that belongs to the cell division cycle 2-like 1 (CDC2L1) subfamily, is associated with cell cycle progression, tumorigenesis and apoptotic signaling. CDK11(p58) is also involved in the regulation of steroid receptors, such as androgen and estrogen receptors....
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138392/ https://www.ncbi.nlm.nih.gov/pubmed/25106495 http://dx.doi.org/10.1186/1471-2407-14-577 |