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Dystrophin deregulation is associated with tumor progression in KIT/PDGFRA mutant gastrointestinal stromal tumors

BACKGROUND: Intragenic deletions of the dystrophin-encoding and muscular dystrophy-associated DMD gene have been recently described in gastrointestinal stromal tumor (GIST), rhabdomyosarcoma (RMS) and leiomyosarcoma (LMS). We evaluated the copy numbers and gene expression levels of DMD in our series...

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Detalles Bibliográficos
Autores principales: Pantaleo, Maria A, Astolfi, Annalisa, Urbini, Milena, Fuligni, Fabio, Saponara, Maristella, Nannini, Margherita, Lolli, Cristian, Indio, Valentina, Santini, Donatella, Ercolani, Giorgio, Brandi, Giovanni, Pinna, Antonio D, Biasco, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138414/
https://www.ncbi.nlm.nih.gov/pubmed/25143820
http://dx.doi.org/10.1186/2045-3329-4-9