Gut-Homing Conventional Plasmablasts and CD27(−) Plasmablasts Elicited after a Short Time of Exposure to an Oral Live-Attenuated Shigella Vaccine Candidate in Humans

Currently, there is no licensed Shigella vaccine; however, various promising live-attenuated vaccine candidates have emerged, including CVD1208S (ΔguaBA, Δset, Δsen S. flexneri 2a), which was shown to be safe and immunogenic in Phase 1 clinical trials. Here, we report the immune responses elicited i...

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Detalles Bibliográficos
Autores principales: Toapanta, Franklin R., Simon, Jakub K., Barry, Eileen M., Pasetti, Marcela F., Levine, Myron M., Kotloff, Karen L., Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138503/
https://www.ncbi.nlm.nih.gov/pubmed/25191323
http://dx.doi.org/10.3389/fimmu.2014.00374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138503/
https://www.ncbi.nlm.nih.gov/pubmed/25191323
http://dx.doi.org/10.3389/fimmu.2014.00374

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