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Oxidative Stress Induces Endothelial Cell Senescence via Downregulation of Sirt6

Accumulating evidence has shown that diabetes accelerates aging and endothelial cell senescence is involved in the pathogenesis of diabetic vascular complications, including diabetic retinopathy. Oxidative stress is recognized as a key factor in the induction of endothelial senescence and diabetic r...

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Detalles Bibliográficos
Autores principales: Liu, Rong, Liu, Hua, Ha, Yonju, Tilton, Ronald G., Zhang, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138737/
https://www.ncbi.nlm.nih.gov/pubmed/25162034
http://dx.doi.org/10.1155/2014/902842