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Comparison of inbred mouse substrains reveals segregation of maladaptive fear phenotypes

Maladaptive fear, such as fear that is persistent or easily generalized to a nonthreatening stimuli, is associated with anxiety-related disorders in humans. In the laboratory, maladaptive fear can be modeled in rodents using Pavlovian fear conditioning. Recently, an inbred mouse strain known as 129S...

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Detalles Bibliográficos
Autores principales: Temme, Stephanie J., Bell, Ryan Z., Pahumi, Reciton, Murphy, Geoffrey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139001/
https://www.ncbi.nlm.nih.gov/pubmed/25191238
http://dx.doi.org/10.3389/fnbeh.2014.00282