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Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters

Concentrative nucleoside transporters (CNTs) are responsible for cellular entry of nucleosides, which serve as precursors to nucleic acids and act as signaling molecules. CNTs also play a crucial role in the uptake of nucleoside-derived drugs, including anticancer and antiviral agents. Understanding...

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Detalles Bibliográficos
Autores principales: Johnson, Zachary Lee, Lee, Jun-Ho, Lee, Kiyoun, Lee, Minhee, Kwon, Do-Yeon, Hong, Jiyong, Lee, Seok-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139061/
https://www.ncbi.nlm.nih.gov/pubmed/25082345
http://dx.doi.org/10.7554/eLife.03604