pH-Induced Conformational Change of IscU at Low pH Correlates with Protonation/Deprotonation of Two Conserved Histidine Residues

[Image: see text] IscU, the scaffold protein for the major iron–sulfur cluster biosynthesis pathway in microorganisms and mitochondria (ISC pathway), plays important roles in the formation of [2Fe–2S] and [4Fe–4S] clusters and their delivery to acceptor apo-proteins. Our laboratory has shown that Is...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Ziqi, Kim, Jin Hae, Tonelli, Marco, Ali, Ibrahim K., Markley, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139155/
https://www.ncbi.nlm.nih.gov/pubmed/25055301
http://dx.doi.org/10.1021/bi500313t

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139155/
https://www.ncbi.nlm.nih.gov/pubmed/25055301
http://dx.doi.org/10.1021/bi500313t

Ejemplares similares