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Structures of KcsA in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site

[Image: see text] Potassium channels allow for the passive movement of potassium ions across the cell membrane and are instrumental in controlling the membrane potential in all cell types. Quaternary ammonium (QA) compounds block potassium channels and have long been used to study the functional and...

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Detalles Bibliográficos
Autores principales: Lenaeus, Michael J., Burdette, Dylan, Wagner, Tobias, Focia, Pamela J., Gross, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139162/
https://www.ncbi.nlm.nih.gov/pubmed/25093676
http://dx.doi.org/10.1021/bi500525s