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Heme Utilization by Pathogenic Bacteria: Not All Pathways Lead to Biliverdin

[Image: see text] The eukaryotic heme oxygenases (HOs) (E.C. 1.14.99.3) convert heme to biliverdin, iron, and carbon monoxide (CO) in three successive oxygenation steps. Pathogenic bacteria require iron for survival and infection. Extracellular heme uptake from the host plays a critical role in iron...

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Detalles Bibliográficos
Autores principales: Wilks, Angela, Ikeda-Saito, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139177/
https://www.ncbi.nlm.nih.gov/pubmed/24873177
http://dx.doi.org/10.1021/ar500028n