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The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production

Hepatitis C virus (HCV) is a considerable global health and economic burden. The HCV nonstructural protein (NS) 5A is essential for the viral life cycle. The ability of NS5A to interact with different host and viral proteins allow it to manipulate cellular pathways and regulate viral processes, incl...

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Detalles Bibliográficos
Autores principales: Eberle, Carol-Ann, Zayas, Margarita, Stukalov, Alexey, Pichlmair, Andreas, Alvisi, Gualtiero, Müller, André C., Bennett, Keiryn L., Bartenschlager, Ralf, Superti-Furga, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139193/
https://www.ncbi.nlm.nih.gov/pubmed/25092459
http://dx.doi.org/10.1016/j.virol.2014.05.016