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Germ Cell Nuclear Factor Regulates Gametogenesis in Developing Gonads

Expression of germ cell nuclear factor (GCNF; Nr6a1), an orphan member of the nuclear receptor gene family of transcription factors, during gastrulation and neurulation is critical for normal embryogenesis in mice. Gcnf represses the expression of the POU-domain transcription factor Oct4 (Pou5f1) du...

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Detalles Bibliográficos
Autores principales: Sabour, Davood, Xu, Xueping, Chung, Arthur C. K., Le Menuet, Damien, Ko, Kinarm, Tapia, Natalia, Araúzo-Bravo, Marcos J., Gentile, Luca, Greber, Boris, Hübner, Karin, Sebastiano, Vittorio, Wu, Guangming, Schöler, Hans R., Cooney, Austin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139263/
https://www.ncbi.nlm.nih.gov/pubmed/25140725
http://dx.doi.org/10.1371/journal.pone.0103985