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Nucleotide-Oligomerization-Domain-2 Affects Commensal Gut Microbiota Composition and Intracerebral Immunopathology in Acute Toxoplasma gondii Induced Murine Ileitis

BACKGROUND: Within one week following peroral high dose infection with Toxoplasma (T.) gondii, susceptible mice develop non-selflimiting acute ileitis due to an underlying Th1-type immunopathology. The role of the innate immune receptor nucleotide-oligomerization-domain-2 (NOD2) in mediating potenti...

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Detalles Bibliográficos
Autores principales: Heimesaat, Markus M., Dunay, Ildiko R., Alutis, Marie, Fischer, André, Möhle, Luisa, Göbel, Ulf B., Kühl, Anja A., Bereswill, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139296/
https://www.ncbi.nlm.nih.gov/pubmed/25141224
http://dx.doi.org/10.1371/journal.pone.0105120