Cargando…

Functional Roles of the Dimer-Interface Residues in Human Ornithine Decarboxylase

Ornithine decarboxylase (ODC) catalyzes the decarboxylation of ornithine to putrescine and is the rate-limiting enzyme in the polyamine biosynthesis pathway. ODC is a dimeric enzyme, and the active sites of this enzyme reside at the dimer interface. Once the enzyme dissociates, the enzyme activity i...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Chien-Yun, Liu, Yi-Liang, Lin, Chih-Li, Liu, Guang-Yaw, Hung, Hui-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139326/
https://www.ncbi.nlm.nih.gov/pubmed/25140796
http://dx.doi.org/10.1371/journal.pone.0104865