Similar Prevalence of Low-Abundance Drug-Resistant Variants in Treatment-Naive Patients with Genotype 1a and 1b Hepatitis C Virus Infections as Determined by Ultradeep Pyrosequencing

BACKGROUND AND OBJECTIVES: Hepatitis C virus (HCV) variants that confer resistance to direct-acting-antiviral agents (DAA) have been detected by standard sequencing technology in genotype (G) 1 viruses from DAA-naive patients. It has recently been shown that virological response rates are higher and...

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Detalles Bibliográficos
Autores principales: Margeridon-Thermet, Severine, Le Pogam, Sophie, Li, Lewyn, Liu, Tommy F., Shulman, Nancy, Shafer, Robert W., Najera, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139363/
https://www.ncbi.nlm.nih.gov/pubmed/25140696
http://dx.doi.org/10.1371/journal.pone.0105569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139363/
https://www.ncbi.nlm.nih.gov/pubmed/25140696
http://dx.doi.org/10.1371/journal.pone.0105569

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