Reducing Igf-1r Levels Leads To Paradoxical and Sexually Dimorphic Effects in HD Mice

Many of the neurodegenerative diseases that afflict people in later life are associated with the formation of protein aggregates. These so-called “proteinopathies” include Alzheimer’s disease (AD) and Huntington’s disease (HD). The insulin/insulin-like growth factor signalling (IIS) pathway has been...

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Detalles Bibliográficos
Autores principales: Corrochano, Silvia, Renna, Maurizio, Osborne, Georgina, Carter, Sarah, Stewart, Michelle, May, Joel, Bates, Gillian P., Brown, Steve D. M., Rubinsztein, David C., Acevedo-Arozena, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139380/
https://www.ncbi.nlm.nih.gov/pubmed/25140802
http://dx.doi.org/10.1371/journal.pone.0105595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139380/
https://www.ncbi.nlm.nih.gov/pubmed/25140802
http://dx.doi.org/10.1371/journal.pone.0105595

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