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Reducing Igf-1r Levels Leads To Paradoxical and Sexually Dimorphic Effects in HD Mice
Many of the neurodegenerative diseases that afflict people in later life are associated with the formation of protein aggregates. These so-called “proteinopathies” include Alzheimer’s disease (AD) and Huntington’s disease (HD). The insulin/insulin-like growth factor signalling (IIS) pathway has been...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139380/ https://www.ncbi.nlm.nih.gov/pubmed/25140802 http://dx.doi.org/10.1371/journal.pone.0105595 |