CRISPR/Cas9-Mediated Gene Knock-Down in Post-Mitotic Neurons

The prokaryotic adaptive immune system CRISPR/Cas9 has recently been adapted for genome editing in eukaryotic cells. This technique allows for sequence-specific induction of double-strand breaks in genomic DNA of individual cells, effectively resulting in knock-out of targeted genes. It thus promise...

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Detalles Bibliográficos
Autores principales: Straub, Christoph, Granger, Adam J., Saulnier, Jessica L., Sabatini, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139396/
https://www.ncbi.nlm.nih.gov/pubmed/25140704
http://dx.doi.org/10.1371/journal.pone.0105584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139396/
https://www.ncbi.nlm.nih.gov/pubmed/25140704
http://dx.doi.org/10.1371/journal.pone.0105584

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