Cargando…
CRISPR/Cas9-Mediated Gene Knock-Down in Post-Mitotic Neurons
The prokaryotic adaptive immune system CRISPR/Cas9 has recently been adapted for genome editing in eukaryotic cells. This technique allows for sequence-specific induction of double-strand breaks in genomic DNA of individual cells, effectively resulting in knock-out of targeted genes. It thus promise...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139396/ https://www.ncbi.nlm.nih.gov/pubmed/25140704 http://dx.doi.org/10.1371/journal.pone.0105584 |