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Recurrent bottlenecks in the malaria life cycle obscure signals of positive selection
Detecting signals of selection in the genome of malaria parasites is a key to identify targets for drug and vaccine development. Malaria parasites have a unique life cycle alternating between vector and host organism with a population bottleneck at each transition. These recurrent bottlenecks could...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139472/ https://www.ncbi.nlm.nih.gov/pubmed/24560397 http://dx.doi.org/10.1017/S0031182014000067 |